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The activation of transcription factors like nuclear factor kappa B (NF-κB) and activator protein-1 (AP-1) by ROS is particularly significant in cancer
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By specifically binding to soluble human TNF‐α, adalimumab effectively inhibits its interaction with cell surface TNF‐α receptors p55 and p75, thereby blocking the inflammatory effects of TNF‐α and achieving successful treatment outcomes
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